Tyieshia McDowell, 47, was killed after being struck by a bullet to the head during a shootout while inside her vehicle at a gas station on Natural Bridge Avenue in St. Louis. The incident occurred the evening of July 31, 2025; first responders found her unconscious but breathing just before 9:15 p.m. and rushed her to a hospital. McDowell, a mother of two and grandmother of one from Florissant, Missouri, died of her injuries on August 2, 2025, and the St. Louis Metropolitan Police Department’s Homicide Division took over the investigation.

Police say she was attempting to flee the shooting when she was fatally wounded. As of the latest reports, investigators have not released information about suspects or a motive and no arrests have been announced. The family arranged her funeral while coping with the sudden loss.

Did anyone see activity at the Natural Bridge Avenue gas station that night or have information that could help investigators?